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Anti-CES3/Carboxylesterase 3 Antibody (5Z251)
还可以产品编号 TMAY-01667
Anti-CES3/Carboxylesterase 3 Antibody (5Z251) 是一种 Mouse 抗体，靶向 CES3/Carboxylesterase 3。Anti-CES3/Carboxylesterase 3 Antibody (5Z251) 可用于 ELISA。
Anti-CES3/Carboxylesterase 3 Antibody (5Z251)
Anti-CES3/Carboxylesterase 3 Antibody (5Z251)
还可以产品编号 TMAY-01667
Anti-CES3/Carboxylesterase 3 Antibody (5Z251) 是一种 Mouse 抗体，靶向 CES3/Carboxylesterase 3。Anti-CES3/Carboxylesterase 3 Antibody (5Z251) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CES3/Carboxylesterase 3 Antibody (5Z251) is a Mouse antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (5Z251) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 5Z251 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CES3 / Carboxylesterase 3 (rh CES3 / Carboxylesterase 3; NP_079198.2Met 1-Glu 561). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carboxylesterases hydrolyze esters of short-chain fatty acids and have roles in animals ranging from signal transduction to xenobiotic detoxification. In enzymology, a carboxylesterase is an enzyme that catalyzes the chemical reaction: a carboxylic ester + H2O = an alcohol + a carboxylate. Most enzymes from this group belong to the superfamily of hydrolases with alpha/beta protein fold (so called Alpha/beta hydrolase fold), specifically those acting on carboxylic ester bonds. The carboxylesterase family of evolutionarily related proteins (those with clear sequence homology to each other) includes a number of proteins with different substrate specificities, such as acetylcholinesterases. Carboxylesterase 3, also known as Liver carboxylesterase 31 homolog and CES3, is a endoplasmic reticulum lumen which belongs to thetype-B carboxylesterase/lipase family. CES3 is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. CES3 shows low catalytic efficiency for hydrolysis of CPT-11, a prodrug for camptothecin used in cancer therapeutics. CES3 is expressed in liver, colon and small intestine. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CES3 / Carboxylesterase 3 protein |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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