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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MEKK3 Antibody (5D33)

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货号 TMAB-08741

Anti-MEKK3 Antibody (5D33) 是一种 Rabbit 抗体，靶向 MEKK3。Anti-MEKK3 Antibody (5D33) 可用于 WB,ICC/IF,FCM。

Anti-MEKK3 Antibody (5D33)

Anti-MEKK3 Antibody (5D33)

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Rating icon 还可以
货号 TMAB-08741

Anti-MEKK3 Antibody (5D33) 是一种 Rabbit 抗体，靶向 MEKK3。Anti-MEKK3 Antibody (5D33) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

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产品描述
Anti-MEKK3 Antibody (5D33) is a Rabbit antibody targeting MEKK3. Anti-MEKK3 Antibody (5D33) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
5D33
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human MEKK3
抗原种属
Human
基因名称
MAP3K3
基因ID
4215
蛋白名称
Mitogen-activated protein kinase kinase kinase 3
Uniprot ID
Q99759
功能
Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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