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Anti-Gbx2 Polyclonal Antibody

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货号 TMAB-06369

Anti-Gbx2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Gbx2。Anti-Gbx2 Polyclonal Antibody 可用于 FCM。

Anti-Gbx2 Polyclonal Antibody

Anti-Gbx2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06369

Anti-Gbx2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Gbx2。Anti-Gbx2 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Gbx2 Polyclonal Antibody is a Rabbit antibody targeting Gbx2. Anti-Gbx2 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes Gbx2 and Otx2. Gbx2 and Otx2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, Gbx2 negatively regulates Otx2 expression along the anterior-posterior axis; Gbx2(-) mutants demonstrate an expanded Otx2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. Gbx2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is over-expressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of Gbx2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that Gbx2 expression may be required for growth of malignant prostate cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Gbx2
抗原种属
Human
基因名称
GBX2
基因ID
蛋白名称
Homeobox protein GBX-2
Uniprot ID
功能
May act as a transcription factor for cell pluripotency and differentiation in the embryo.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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