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Tat-ASIC1a (1-20) (mouse, rat) 是一种能够对抗ASIC1a的跨膜肽,具有神经保护特性。它通过靶向ASIC1a-RIPK1通路和自身调节机制,减少酸性毒性引起的神经元损伤。在缺血性中风的小鼠模型中,Tat-ASIC1a (1-20) (mouse, rat) 能有效减少大脑的缺血性损害。此化合物适用于研究诸如Huntington disease和Parkinson’s disease等神经退行性疾病。
Tat-ASIC1a (1-20) (mouse, rat) 是一种能够对抗ASIC1a的跨膜肽,具有神经保护特性。它通过靶向ASIC1a-RIPK1通路和自身调节机制,减少酸性毒性引起的神经元损伤。在缺血性中风的小鼠模型中,Tat-ASIC1a (1-20) (mouse, rat) 能有效减少大脑的缺血性损害。此化合物适用于研究诸如Huntington disease和Parkinson’s disease等神经退行性疾病。

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | 待询 | 待询 | |
| 50 mg | 待询 | 待询 |
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| 产品描述 | Tat-ASIC1a (1-20) (mouse, rat) is a competitive ASIC1a transmembrane peptide with significant neuroprotective effects. It alleviates acidotoxic neuronal damage by targeting the ASIC1a-RIPK1 pathway and an auto-inhibition mechanism. This compound effectively safeguards the brain in ischemic stroke mouse models against damage from ischemia and is applicable in research on neurodegenerative diseases, such as Huntington's disease and Parkinson’s disease. |
| Sequence | Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Met-Glu-Leu-Lys-Thr-Glu-Glu-Glu-Glu-Val-Gly-Gly-Val-Gln-Pro-Val-Ser-Ile-Gln-Ala |
| Sequence Short | GRKKRRQRRRCMELKTEEEEVGGVQPVSIQA |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多