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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Desmin Antibody (6S357)

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货号 TMAB-05095

Anti-Desmin Antibody (6S357) 是一种 Rabbit 抗体，靶向 Desmin。Anti-Desmin Antibody (6S357) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Desmin Antibody (6S357)

Anti-Desmin Antibody (6S357)

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Rating icon 还可以
货号 TMAB-05095

Anti-Desmin Antibody (6S357) 是一种 Rabbit 抗体，靶向 Desmin。Anti-Desmin Antibody (6S357) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Desmin Antibody (6S357) is a Rabbit antibody targeting Desmin. Anti-Desmin Antibody (6S357) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
6S357
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:1000-5000; IHC-P: 1:200-800; IHC-Fr: 1:200-800; ICC/IF: 1:100-500; IF: 1:200-800
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Desmin is a muscle-specific, type III intermediate filament that integrates the sarcolemma, Z disk, and nuclear membrane in sarcomeres and regulates sarcomere architecture. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin antibodies are useful in identification of tumours of myogenic origin
抗原信息
免疫原
A synthesized peptide: human Desmin
抗原种属
Human
基因名称
DES
基因ID
1674
蛋白名称
Desmin
Uniprot ID
P17661
功能
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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