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Gankyrin Protein, Human, Recombinant

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货号 TMPJ-00703

别名 PSMD10, p28(GANK), Gankyrin, 26S Proteasome Regulatory Subunit p28, 26S Proteasome Non-ATPase Regulatory Subunit 10

Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.

Gankyrin Protein, Human, Recombinant
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Gankyrin Protein, Human, Recombinant

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Rating icon 还可以
货号 TMPJ-00703 别名 PSMD10, p28(GANK), Gankyrin, 26S Proteasome Regulatory Subunit p28, 26S Proteasome Non-ATPase Regulatory Subunit 10

Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.

规格价格库存数量
5 μg
¥ 492
6-8日内发货
10 μg
¥ 820
6-8日内发货
20 μg
¥ 1,290
5日内发货
50 μg
¥ 2,480
5日内发货
100 μg
¥ 3,980
5日内发货
200 μg
¥ 6,420
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 17,300
5日内发货
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产品介绍


生物活性
产品描述
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号O75832
氨基酸序列Met1-Gly226
蛋白构建Met1-Gly226
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
别名PSMD10, p28(GANK), Gankyrin, 26S Proteasome Regulatory Subunit p28, 26S Proteasome Non-ATPase Regulatory Subunit 10
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量26 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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