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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL-16 Polyclonal Antibody

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货号 TMAB-07608

Anti-IL-16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-16。Anti-IL-16 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,ELISA。

Anti-IL-16 Polyclonal Antibody

Anti-IL-16 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07608

Anti-IL-16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-16。Anti-IL-16 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-16 Polyclonal Antibody is a Rabbit antibody targeting IL-16. Anti-IL-16 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFELISA
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted (By similarity). Isoform 1: Cytoplasm. Note=Colocalizes with GRIN2C in neuronal cell bodies and neurites. Isoform 2: Cytoplasm. Nucleus (By similarity).
组织特异性Isoform 1 is expressed in neurons of the cerebellum and hippocampus. Isoform 2 is expressed in thymus, spleen and lung.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
抗原信息
免疫原
Recombinant Protein: human IL16 protein
抗原种属
Human
基因名称
IL16
基因ID
3603
蛋白名称
Pro-interleukin-16
Uniprot ID
Q14005
功能
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
化学信息
分子量Theoretical: 142 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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