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Anti-C3orf15 Polyclonal Antibody

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货号 TMAB-03426

Anti-C3orf15 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 C3orf15。Anti-C3orf15 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-C3orf15 Polyclonal Antibody

Anti-C3orf15 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03426

Anti-C3orf15 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 C3orf15。Anti-C3orf15 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-C3orf15 Polyclonal Antibody is a Rabbit antibody targeting C3orf15. Anti-C3orf15 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Mitochondrion. Isoform 4 is found in the mitochondria and localized in the neck of the sperm.
组织特异性Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The c-Myc proto-oncogene plays a significant role in cell proliferation, differentiation, transformation and apoptosis. A novel c-Myc binding protein, MYCBP (also designated AMY-1), binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. MYCBP translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. MYCBP and AAT-1 (AMY-1-associating protein expressed in testis 1) have been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP and AAT-1 in spermatogenesis. Expression of the AAT-1 gene is regulated by two different promoters, which result in various isoforms. One promoter generates expression of the AAT-1, AAT-1å, AAT-1∫ and AAT-1© isoforms, which are specifically expressed in testis, while the other promoter generates AAT-1L, AAT-1M and AAT-1S, which are differentially expressed.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AAT1/C3orf15
抗原种属
Human
基因名称
CFAP91
基因ID
蛋白名称
Cilia-and flagella-associated protein 91
Uniprot ID
功能
Isoform 4 may play a role in spermatogenesis.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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