Anti-CD2 Antibody (8W59)

Name: Anti-CD2 Antibody (8W59)
Brand: TargetMol
SKU: TMAY-01418
Rating: 4.5 (1 reviews)

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产品编号 TMAY-01418

Anti-CD2 Antibody (8W59) 是一种 Mouse 抗体，靶向 CD2。Anti-CD2 Antibody (8W59) 可用于 FCM。

Anti-CD2 Antibody (8W59)

还可以

产品编号 TMAY-01418

Anti-CD2 Antibody (8W59) 是一种 Mouse 抗体，靶向 CD2。Anti-CD2 Antibody (8W59) 可用于 FCM。

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生物活性

产品描述	Anti-CD2 Antibody (8W59) is a Mouse antibody targeting CD2. Anti-CD2 Antibody (8W59) can be used in FCM.
Ig Type	Monoclonal Mouse IgG1
克隆号	8W59
交叉反应	Human
验证活性	Flow cytometric analysis of Human CD2 expression on human peripheral blood lymphocytes. Cells were stained with purified Mouse anti-Human CD2, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of viable lymphocytes.
应用	FCM
推荐剂量	FCM: 1:25-1:100
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This product is a recombinant monoclonal antibody expressed from HEK293 cells.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated
其他可选修饰符	APC/PerCP/FITC/PE
可提供抗体种类	5

抗原信息

免疫原	Recombinant Human CD2 protein (TMPY-01255)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.