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Anti-TYMS Antibody (8R369)
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产品编号 TMAC-04037
别名 TSase, TS, Thymidylate synthase, EC 2.1.1.45
Anti-TYMS Antibody (8R369) 是一种 Rabbit 抗体，靶向 TYMS。Anti-TYMS Antibody (8R369) 可用于 WB,IHC,IP,FCM。
Anti-TYMS Antibody (8R369)
Anti-TYMS Antibody (8R369)
还可以产品编号 TMAC-04037 别名 TSase, TS, Thymidylate synthase, EC 2.1.1.45
Anti-TYMS Antibody (8R369) 是一种 Rabbit 抗体，靶向 TYMS。Anti-TYMS Antibody (8R369) 可用于 WB,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-TYMS Antibody (8R369) is a Rabbit antibody targeting TYMS. Anti-TYMS Antibody (8R369) can be used in WB,IHC,IP,FCM. |
| 别名 | TSase, TS, Thymidylate synthase, EC 2.1.1.45 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Thymidylate Synthase on different cell lysate using anti-Thymidylate Synthase antibody at 1/1,000 dilution. Positive control: Lane1: Hela, Lane2: Jurkat, Lane3: Raji, Lane4: Mouse testes, Lane5: Mouse brain, Lane6: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded rat bone tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of Hela cells with Thymidylate Synthase antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Thymidylate synthase (TS), also designated TYMS, TMS, TSase and HsT422, uses 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor in the synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor for DNA biosynthesis. TS is an RNA-binding protein that can interact with its own mRNA. The TS/mRNA ribonucleoprotein complex can also associate with a number of other cellular mRNAs, including those corresponding to the p53 tumor suppressor gene and the Myc family of transcription factors. Inhibition of DNA replication and cell death resulting from thymidine depletion occurs when TS enzyme activity is inhibited with substrate or cofactor analogs, making the TS enzyme an important target for chemotherapy. Cancer cells are sensitive to thymidine depletion, as they multiply rapidly. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 36 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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