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Anti-METTL3 Antibody (6N3) 是一种 Rabbit 抗体,靶向 METTL3。Anti-METTL3 Antibody (6N3) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
Anti-METTL3 Antibody (6N3) 是一种 Rabbit 抗体,靶向 METTL3。Anti-METTL3 Antibody (6N3) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-METTL3 Antibody (6N3) is a Rabbit antibody targeting METTL3. Anti-METTL3 Antibody (6N3) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| 克隆号 | 6N3 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrICC/IFIFIPFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus speckle. Colocalizes with speckles in interphase nuclei. Suggesting that it may be associated with nuclear pre-mRNA splicing components. |
| 组织特异性 | Widely expressed at low level. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some RNAs and regulates various processes such as the circadian clock, differentiation of embryonic and hematopoietic stem cells, cortical neurogenesis, response to DNA damage, differentiation of T-cells and primary miRNA processing. |
| 免疫原 | A synthesized peptide: human METTL3 |
| 抗原种属 | Human |
| 基因名称 | METTL3 |
| 基因ID | |
| 蛋白名称 | N6-adenosine-methyltransferase catalytic subunit |
| Uniprot ID | |
| 功能 | N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation. |
| 分子量 | Theoretical: 64 kDa. Actual: 70 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |