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Anti-IL-1RA Antibody (9J104)
还可以产品编号 TMAY-00306
Anti-IL-1RA Antibody (9J104) 是一种 Rabbit 抗体，靶向 IL-1RA。Anti-IL-1RA Antibody (9J104) 可用于 ELISA。
Anti-IL-1RA Antibody (9J104)
Anti-IL-1RA Antibody (9J104)
还可以产品编号 TMAY-00306
Anti-IL-1RA Antibody (9J104) 是一种 Rabbit 抗体，靶向 IL-1RA。Anti-IL-1RA Antibody (9J104) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-1RA Antibody (9J104) is a Rabbit antibody targeting IL-1RA. Anti-IL-1RA Antibody (9J104) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9J104 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL1RA (rh IL1RA; TMPY-00853; NP_776214.1; Arg 26-Glu 177) . |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of this protein-encoding gene is reported to be associated with an increased risk of osteoporotic fractures and gastric cancer. IL-1RA/IL1RN may inhibit the activity of IL-1 by binding to its receptor and it has no IL-1 like activity. Genetic variation in IL-1RA/IL1RN is associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4). These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Defects in IL-1RA/IL1RN are the cause of interleukin 1 receptor antagonist deficiency (DIRA) which is also known as deficiency of interleukin 1 receptor antagonist. Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T-cells. DIRA is a rare, autosomal recessive, genetic autoinflammatory disease that results in sterile multifocal osteomyelitis, and pustulosis from birth. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL1RA protein (TMPY-00853) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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