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Anti-CD166/ALCAM Antibody (5E235)
还可以产品编号 TMAY-03905
别名 MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody (5E235) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5E235) 可用于 WB。
Anti-CD166/ALCAM Antibody (5E235)
Anti-CD166/ALCAM Antibody (5E235)
还可以产品编号 TMAY-03905 别名 MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody (5E235) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5E235) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-CD166/ALCAM Antibody (5E235) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5E235) can be used in WB. |
| 别名 | MEMD, CD166, activated leukocyte cell adhesion molecule |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5E235 |
| 交叉反应 | Cynomolgus |
| 验证活性 | Anti-ALCAM rabbit monoclonal antibody at 1:500 dilution. -Lane A: HuT78 Whole Cell Lysate. -Lane B: Daudi Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:65 kDa. -Observed band size:65 kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus CD166 / ALCAM (TMPY-03520; G7NZQ8; Met1-Ala526). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Cynomolgus CD166 / ALCAM protein (TMPY-03520) |
| 抗原种属 | Cynomolgus |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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