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Anti-FPGS Antibody (7Z220) 是一种抗体,靶向 FPGS。Anti-FPGS Antibody (7Z220) 可用于 ELISA, FC。
Anti-FPGS Antibody (7Z220) 是一种抗体,靶向 FPGS。Anti-FPGS Antibody (7Z220) 可用于 ELISA, FC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,305 | 5日内发货 | |
100 μL | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-FPGS Antibody (7Z220) is an antibody targeting FPGS. Anti-FPGS Antibody (7Z220) can be used in ELISA, FC. |
别名 | Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase, mitochondrial, Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, EC 6.3.2.17 |
Ig Type | Rabbit IgG |
克隆号 | 7Z220 |
交叉反应 | Human |
验证活性 | Overlay Peak curve showing HepG2 cells stained with TMAH-00457 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
应用 | ELISA, FC |
推荐剂量 | FC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | [Isoform 1]: Mitochondrion inner membrane. Mitochondrion matrix.; [Isoform 2]: Cytoplasm. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human FPGS |
抗原种属 | Human |
基因ID | 2356 |
Uniprot ID | |
研究领域 | Metabolism, Signal transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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