Azobenzene

Name: Azobenzene
Brand: TargetMol
SKU: T0609
Rating: 4.5 (1 reviews)

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很棒

纯度: 98.45%

货号 T0609Cas号 103-33-3

别名 偶氮苯, Diphenyldiazene, Diazene

Azobenzene是一种光触发器，可用于设计和合成各种光响应系统。Azobenzene 具有遗传毒性，可诱发脾脏和其他腹部器官的侵袭性肉瘤。

Azobenzene

一键复制产品信息

很棒

纯度: 98.45%

货号 T0609 别名 偶氮苯, Diphenyldiazene, DiazeneCas号 103-33-3

Azobenzene是一种光触发器，可用于设计和合成各种光响应系统。Azobenzene 具有遗传毒性，可诱发脾脏和其他腹部器官的侵袭性肉瘤。

规格	价格	库存	数量
500 mg	¥ 99	待询
1 mL x 10 mM (in DMSO)	¥ 99	现货

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产品介绍

Azobenzene AI Summary

Azobenzene exhibits a high capacity ratio with a log k'w value of 3.961, indicating good retention on the stationary phase in chromatographic processes, and a logP value of 3.82, suggesting moderate lipophilicity. The compound shows a strong binding affinity to bovine serum albumin with a log 1/C value of 5.29, indicating potential for significant protein binding interactions. Azobenzene does not inhibit 17-alpha-hydroxylase/17,20 lyase from rat testes microsomes at a concentration of 100 μM. It demonstrates bioactivity in assays related to cell viability and metabolic activity with potencies ranging from 631.0 nM to 79432.8 nM. The compound also exhibits inhibitory effects on aldehyde dehydrogenase 1 (ALDH1A1), glucocorticoid receptor signaling, antioxidant response element (ARE) signaling pathway, and human apurinic/apyrimidinic endonuclease 1 (APE1). Additionally, Azobenzene significantly inhibits sodium fluorescein uptake in both OATP1B3-transfected and OATP1B1-transfected CHO cells, with inhibition percentages of 112.1% and 216.34% respectively, at an equimolar substrate-inhibitor concentration of 10 μM. It shows high solubility in water when irradiated with 365 nm UV light for up to 10 minutes and has a half-life of 48 hours in water under these conditions, as determined by UV-Visible spectrum analysis and 1H NMR analysis. These properties suggest that Azobenzene may significantly interact with chromatographic systems, biomolecules, and transporters, influencing its pharmacokinetic and pharmacodynamic profiles..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Azobenzene is a phototrigger that can be used to design and synthesize a variety of photoresponsive systems.Azobenzene is genotoxic and induces aggressive sarcomas of the spleen and other abdominal organs.
别名	偶氮苯, Diphenyldiazene, Diazene

化学信息

分子量	182.22
分子式	C₁₂H₁₀N₂
CAS No.	103-33-3
Smiles	c1ccc(cc1)\N=N\c1ccccc1
密度	1.09 g/cm3 at 25℃ (lit.)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 150 mg/mL (823.18 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4879 mL	27.4394 mL	54.8787 mL	274.3936 mL
5 mM	1.0976 mL	5.4879 mL	10.9757 mL	54.8787 mL
10 mM	0.5488 mL	2.7439 mL	5.4879 mL	27.4394 mL
20 mM	0.2744 mL	1.3720 mL	2.7439 mL	13.7197 mL
50 mM	0.1098 mL	0.5488 mL	1.0976 mL	5.4879 mL
100 mM	0.0549 mL	0.2744 mL	0.5488 mL	2.7439 mL