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Anti-DHX58 Antibody (1Q521)
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产品编号 TMAC-01146
别名 RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2
Anti-DHX58 Antibody (1Q521) 是一种 Mouse 抗体，靶向 DHX58。Anti-DHX58 Antibody (1Q521) 可用于 WB,FCM。
Anti-DHX58 Antibody (1Q521)
Anti-DHX58 Antibody (1Q521)
还可以产品编号 TMAC-01146 别名 RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2
Anti-DHX58 Antibody (1Q521) 是一种 Mouse 抗体，靶向 DHX58。Anti-DHX58 Antibody (1Q521) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,990 | 5日内发货 | |
| 100 μL | ¥ 2,980 | 5日内发货 |
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| 产品描述 | Anti-DHX58 Antibody (1Q521) is a Mouse antibody targeting DHX58. Anti-DHX58 Antibody (1Q521) can be used in WB,FCM. |
| 别名 | RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of DHX58 on human DHX58 recombinant protein using anti-DHX58 antibody at 1/1,000 dilution. 2. Western blot analysis of DHX58 on HEK293 (1) and DHX58-hIgGFc transfected HEK293 (2) cell lysate using anti-DHX58 antibody at 1/1,000 dilution. 3. Flow cytometric analysis of Hela cells with DHX58 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Helicases are enzymes that catalyze the separation of double stranded DNA or RNA by utilizing ATP. LGP2, also known as probable ATP-dependent RNA helicase DHX58, is a 678 amino acid protein belonging to the helicase family. LGP2 acts as a negative regulator of host innate immune defense against viruses by binding dsRNA produced during viral replication. The repressor domain of LGP2 binds to RIG-I, a signaling protein involved in host defenses against hepatitis C virus (HCV). By preventing RIG-I multimerization, LGP2 negatively regulates RIG-I-mediated signaling. Localized to the cytoplasm, LGP2 contains one helicase ATP-binding domain and one helicase C-terminal domain. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 77 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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