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Anti-ECRG4 Polyclonal Antibody

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货号 TMAB-05427

Anti-ECRG4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ECRG4。Anti-ECRG4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ECRG4 Polyclonal Antibody

Anti-ECRG4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05427

Anti-ECRG4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ECRG4。Anti-ECRG4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-ECRG4 Polyclonal Antibody is a Rabbit antibody targeting ECRG4. Anti-ECRG4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Cytoplasmic vesicle, secretory vesicle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ECRG4, also known as augurin or C2orf40, is a 148 amino acid secreted protein. Belonging to the augurin family, ECRG4 is thought to be a hormone. It has also been suggested that ECRG4 may act as a tumor suppressor. The gene that encodes ECRG4 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ECRG4/C2orf40
抗原种属
Human
基因名称
ECRG4
基因ID
蛋白名称
Augurin
Uniprot ID
功能
Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.
化学信息
分子量Theoretical: 7.8 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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