- 全部删除
- 您的购物车当前为空
Anti-ITGAX Antibody (6V627) 是一种 Mouse 抗体,靶向 ITGAX。Anti-ITGAX Antibody (6V627) 可用于 WB,IP,IF,IHC-P。
Anti-ITGAX Antibody (6V627) 是一种 Mouse 抗体,靶向 ITGAX。Anti-ITGAX Antibody (6V627) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-ITGAX Antibody (6V627) is a Mouse antibody targeting ITGAX. Anti-ITGAX Antibody (6V627) can be used in WB,IP,IF,IHC-P. |
别名 | SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C |
克隆号 | 6V627 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Integrin αX expression in non-transfected 293T (A), human Integrin αX transfected 293T (B) and HL-60 (C) whole cell. 2. Western blot analysis of Integrin αX expression in AML-193 whole cell lysate. |
应用 | |
推荐剂量 | WB: 1:100-10000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrin ?X (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with ∫2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin ?X/∫2 shares similar properties of the ?M/∫2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin ?X is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin ?X include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin ?X is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response. |
偶联 | Unconjugated |
免疫原 | Peptide |
Uniprot ID |
分子量 | Theoretical: 145 kDa. |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
运输方式 | Shipping with blue ice. |
评论内容