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Anti-ITGAX Antibody (6V627)

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Anti-ITGAX Antibody (6V627)
产品编号 TMAC-00650
别名 SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C

Anti-ITGAX Antibody (6V627) 是一种 Mouse 抗体,靶向 ITGAX。Anti-ITGAX Antibody (6V627) 可用于 WB,IP,IF,IHC-P。

Anti-ITGAX Antibody (6V627)

Anti-ITGAX Antibody (6V627)

Rating icon 还可以
Anti-ITGAX Antibody (6V627)
产品编号 TMAC-00650 别名 SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C

Anti-ITGAX Antibody (6V627) 是一种 Mouse 抗体,靶向 ITGAX。Anti-ITGAX Antibody (6V627) 可用于 WB,IP,IF,IHC-P。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-ITGAX Antibody (6V627) is a Mouse antibody targeting ITGAX. Anti-ITGAX Antibody (6V627) can be used in WB,IP,IF,IHC-P.
别名SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C
克隆号
6V627
交叉反应
Human
验证活性
1. Western blot analysis of Integrin αX expression in non-transfected 293T (A), human Integrin αX transfected 293T (B) and HL-60 (C) whole cell.
2. Western blot analysis of Integrin αX expression in AML-193 whole cell lysate.
应用
推荐剂量
WB: 1:100-10000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Integrin ?X (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with ∫2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin ?X/∫2 shares similar properties of the ?M/∫2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin ?X is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin ?X include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin ?X is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide
Uniprot ID
化学信息
分子量Theoretical: 145 kDa.
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze.
运输方式Shipping with blue ice.

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