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Anti-MAP2 Antibody (9V59)

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Anti-MAP2 Antibody (9V59)
产品编号 TMAY-00518
别名 p67eIF2, p67, MNPEP, MAP2

Anti-MAP2 Antibody (9V59) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (9V59) 可用于 WB。

Anti-MAP2 Antibody (9V59)
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Anti-MAP2 Antibody (9V59)

Rating icon 还可以
Anti-MAP2 Antibody (9V59)
产品编号 TMAY-00518 别名 p67eIF2, p67, MNPEP, MAP2

Anti-MAP2 Antibody (9V59) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (9V59) 可用于 WB。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAP2 Antibody (9V59) is a Mouse antibody targeting MAP2. Anti-MAP2 Antibody (9V59) can be used in WB.
别名p67eIF2, p67, MNPEP, MAP2
Ig Type
Mouse IgG1
克隆号
9V59
交叉反应
Human
验证活性
Anti-METAP2 mouse monoclonal antibody at 1:500 dilution.
-Lane A: HepG2 Whole Cell Lysate.
-Lane B: PC12 Whole Cell Lysate.
-Lane C: Jurkat Whole Cell Lysate.
-Lane D: A431 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Rabbit Anti-Mouse IgG F(ab)2/HRP at 1/10000 dilution.
-Developed using the ECL technique.
-Performed under reducing conditions.
-Predicted band size:52 kDa.
-Observed band size:60 kDa
应用
WB
推荐剂量
WB: 1:500-1:1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAP2 (rh MAP2; TMPY-00018; NP_006829.1; Met1-Tyr478). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景METAP2 (Methionine aminopeptidase 2), also known as MAP2 is a protein that belongs to the peptidase M24A family. MAP2 binds 2 cobalt or manganese ions and contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. It is found in all organisms and is especially important because of its critical role in tissue repair and protein degradation. The catalytic activity of human MAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. MAP2 protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. It also plays a critical role in the regulation of protein synthesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human MAP2 Protein (TMPY-00018)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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