Anti-MAP2 Antibody (9V59)

Name: Anti-MAP2 Antibody (9V59)
Brand: TargetMol
SKU: TMAY-00518
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00518

Anti-MAP2 Antibody (9V59) 是一种 Mouse 抗体，靶向 MAP2。Anti-MAP2 Antibody (9V59) 可用于 WB。

Anti-MAP2 Antibody (9V59)

还可以

产品编号 TMAY-00518

Anti-MAP2 Antibody (9V59) 是一种 Mouse 抗体，靶向 MAP2。Anti-MAP2 Antibody (9V59) 可用于 WB。

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生物活性

产品描述	Anti-MAP2 Antibody (9V59) is a Mouse antibody targeting MAP2. Anti-MAP2 Antibody (9V59) can be used in WB.
Ig Type	Monoclonal Mouse IgG1
克隆号	9V59
交叉反应	Human
验证活性	Anti-METAP2 mouse monoclonal antibody at 1:500 dilution. -Lane A: HepG2 Whole Cell Lysate. -Lane B: PC12 Whole Cell Lysate. -Lane C: Jurkat Whole Cell Lysate. -Lane D: A431 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Rabbit Anti-Mouse IgG F(ab)2/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:52 kDa. -Observed band size:60 kDa
应用	WB
推荐剂量	WB: 1:500-1:1000
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAP2 (rh MAP2; TMPY-00018; NP_006829.1; Met1-Tyr478). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	METAP2 (Methionine aminopeptidase 2), also known as MAP2 is a protein that belongs to the peptidase M24A family. MAP2 binds 2 cobalt or manganese ions and contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. It is found in all organisms and is especially important because of its critical role in tissue repair and protein degradation. The catalytic activity of human MAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. MAP2 protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. It also plays a critical role in the regulation of protein synthesis.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human MAP2 Protein (TMPY-00018)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.