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HMBS Protein, Human, Recombinant (His)

HMBS Protein, Human, Recombinant (His)

产品编号 TMPJ-00806
别名: Pre-Uroporphyrinogen Synthase, PBG-D, Hydroxymethylbilane Synthase, PBGD, Porphobilinogen Deaminase, HMBS, UPS

Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.

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HMBS Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: HMBS Protein, Human, Recombinant (His) (TMPJ-00806)
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产品描述 Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
种属 Human
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 P08397
别名 Pre-Uroporphyrinogen Synthase, PBG-D, Hydroxymethylbilane Synthase, PBGD, Porphobilinogen Deaminase, HMBS, UPS
氨基酸序列 Ser2-His361
蛋白构建 Ser2-His361
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 47 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5% Trehalose, 5% mannitol, 50% Glycerol, 0.1% Tween 80, pH7.4.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.

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Keywords

HMBS Protein, Human, Recombinant (His) Pre-Uroporphyrinogen Synthase PBG-D Hydroxymethylbilane Synthase PBGD Porphobilinogen Deaminase HMBS UPS recombinant recombinant-proteins proteins protein

 

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