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Anti-C17ORF53 Antibody (1Z939)
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产品编号 TMAC-00502
别名 Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53
Anti-C17ORF53 Antibody (1Z939) 是一种 Mouse 抗体，靶向 C17ORF53。Anti-C17ORF53 Antibody (1Z939) 可用于 WB,ICC,FCM。
Anti-C17ORF53 Antibody (1Z939)
Anti-C17ORF53 Antibody (1Z939)
还可以产品编号 TMAC-00502 别名 Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53
Anti-C17ORF53 Antibody (1Z939) 是一种 Mouse 抗体，靶向 C17ORF53。Anti-C17ORF53 Antibody (1Z939) 可用于 WB,ICC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,995 | 5日内发货 | |
| 100 μL | ¥ 2,985 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-C17ORF53 Antibody (1Z939) is a Mouse antibody targeting C17ORF53. Anti-C17ORF53 Antibody (1Z939) can be used in WB,ICC,FCM. |
| 别名 | Uncharacterized protein C17orf53, MGC3130, Hypothetical protein LOC78995, FLJ11594, CQ053_HUMAN, Chromosome 17 open reading frame 53, C17orf53 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of C17ORF53 on human C17ORF53 recombinant protein using anti-C17ORF53 antibody at 1/1,000 dilution. 2. Western blot analysis of C17ORF53 on HEK293 (1) and C17ORF53-hIgGFc transfected HEK293 (2) cell lysate using anti-C17ORF53 antibody at 1/1,000 dilution. 3. ICC staining C17ORF53 (green) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Jurkat cells with C17ORF53 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; ICC: 1:50-200; FCM: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| 研究背景 | C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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