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CYP11B2 Protein, Human, Recombinant (His & SUMO)

CYP11B2 Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-01181
别名: ALDOS, Corticosterone 18-monooxygenase, CYP11B2, Aldosterone synthase, CYPXIB2, Cytochrome P-450Aldo, Aldosterone-synthesizing enzyme, CYP11B2, Cytochrome P450 11B2, mitochondrial

CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

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CYP11B2 Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,800 20日内发货
100 μg ¥ 3,420 20日内发货
1 mg ¥ 14,600 20日内发货
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产品目录号及名称: CYP11B2 Protein, Human, Recombinant (His & SUMO) (TMPH-01181)
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生物活性
技术参数
产品性质
产品描述 CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-6xHis-SUMO
蛋白编号 P19099
别名 ALDOS, Corticosterone 18-monooxygenase, CYP11B2, Aldosterone synthase, CYPXIB2, Cytochrome P-450Aldo, Aldosterone-synthesizing enzyme, CYP11B2, Cytochrome P450 11B2, mitochondrial
氨基酸序列 GTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN
蛋白构建 25-503
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 71.0 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 A cytochrome P450 monooxygenase that catalyzes the biosynthesis of adrenal mineralocorticoid aldosterone. Catalyzes three sequential oxidative reactions of 11-deoxycorticosterone/21-hydroxyprogesterone, namely 11-beta hydroxylation followed with two successive oxidations at C18 to yield 18-hydroxy and then 18-aldehyde derivatives, resulting in the formation of aldosterone. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).

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Keywords

CYP11B2 Protein, Human, Recombinant (His & SUMO) ALDOS Corticosterone 18-monooxygenase, CYP11B2 Aldosterone synthase CYPXIB2 Cytochrome P-450Aldo Aldosterone-synthesizing enzyme CYP11B2 Cytochrome P450 11B2, mitochondrial recombinant recombinant-proteins proteins protein

 

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