购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空

M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3)

产品编号 TMPY-07077

M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3) is expressed in HEK293 Cells. The accession number is P09603-3.

M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3)

M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3)

产品编号 TMPY-07077
M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3) is expressed in HEK293 Cells. The accession number is P09603-3.
规格价格库存数量
20 μg
¥ 1,750
期货
100 μg
¥ 4,420
期货
1 mg 询价 期货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多

产品信息

生物活性
Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 3-15 ng/mL.
产品描述
M-CSF/CSF1 Protein, Human, Recombinant (Isoform 3) is expressed in HEK293 Cells. The accession number is P09603-3.
种属
Human
表达系统
HEK293 Cells
标签Tag Free
蛋白编号P09603-3
别名
PG-M-CSF,MGC31930,M-CSF,MCSF,CSF-1
蛋白构建
A DNA sequence encoding the Human CSF1 (P09603-3) (Met1-Ser190) was expressed.
蛋白纯度
≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
分子量18.41 kDa (predicted); 21.8 kDa and 19.3 kDa (reducing contition)
内毒素< 10 EU per mg of the protein.
缓冲液Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法
Please refer to the lot-specific COA.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.