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Anti-PER2 Antibody (5Q737) 是一种 Rabbit 抗体,靶向 PER2。Anti-PER2 Antibody (5Q737) 可用于 WB,ICC/IF,FCM。
Anti-PER2 Antibody (5Q737) 是一种 Rabbit 抗体,靶向 PER2。Anti-PER2 Antibody (5Q737) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-PER2 Antibody (5Q737) is a Rabbit antibody targeting PER2. Anti-PER2 Antibody (5Q737) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 5Q737 |
| 反应种属 | Human |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. Mainly nuclear. Nucleocytoplasmic shuttling is effected by interaction with other circadian core oscillator proteins and/or by phosphorylation. Retention of PER1 in the cytoplasm occurs through PER1-PER2 heterodimer formation or by interaction with CSNK1E and/or phosphorylation which appears to mask the PER nuclear localization signal. Also translocated to the nucleus by CRY1 or CRY2. |
| 组织特异性 | Widely expressed. Found in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. High levels in skeletal muscle and pancreas. Low level in lung. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. |
| 免疫原 | A synthesized peptide: human PER2 |
| 抗原种属 | Human |
| 基因名称 | PER2 |
| 基因ID | |
| 蛋白名称 | Period circadian protein homolog 2 |
| Uniprot ID | |
| 功能 | Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK NPAS2-BMAL1 |
| 分子量 | Theoretical: 137 kDa. Actual: 137 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |