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别名 Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1
Anti-UGRP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UGRP1。Anti-UGRP1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P。
Anti-UGRP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UGRP1。Anti-UGRP1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-UGRP1 Polyclonal Antibody is a Rabbit antibody targeting UGRP1. Anti-UGRP1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P. |
| 别名 | Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1 |
| Ig Type | IgG |
| 反应种属 | (predicted:Human,Mouse,Rat,Pig,Horse) |
| 应用 | ICC/IFIFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation |
| 免疫原 | KLH conjugated synthetic peptide: human SCGB3A2 |
| 抗原种属 | Human |
| 基因名称 | SCGB3A2 |
| 基因ID | |
| 蛋白名称 | Secretoglobin family 3A member 2 |
| Uniprot ID | |
| 研究领域 | Other factors |
| 功能 | In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1. |
| 分子量 | Theoretical: 8 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |