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Anti-UGRP1 Polyclonal Antibody

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货号 TMAB-01932

别名 Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1

Anti-UGRP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UGRP1。Anti-UGRP1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P。

Anti-UGRP1 Polyclonal Antibody

Anti-UGRP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01932 别名 Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1

Anti-UGRP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UGRP1。Anti-UGRP1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-UGRP1 Polyclonal Antibody is a Rabbit antibody targeting UGRP1. Anti-UGRP1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P.
别名Uteroglobin-Related Protein 1, UGRP1, Secretoglobin Family 3A Member 2, SCGB3A2, PnSP-1, PNSP1, Pneumo Secretory Protein 1
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Pig,Horse)
应用ICC/IFIFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation
抗原信息
免疫原
KLH conjugated synthetic peptide: human SCGB3A2
抗原种属
Human
基因名称
SCGB3A2
基因ID
蛋白名称
Secretoglobin family 3A member 2
Uniprot ID
研究领域
Other factors
功能
In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1.
化学信息
分子量Theoretical: 8 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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