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Anti-CD19 Antibody-FITC (1T602)

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产品编号 TMAY-02131F

Anti-CD19 Antibody-FITC (1T602) 是一种 FITC-conjugated Mouse 抗体,靶向 CD19。Anti-CD19 Antibody-FITC (1T602) 可用于 FCM。

Anti-CD19 Antibody-FITC (1T602)

Anti-CD19 Antibody-FITC (1T602)

Rating icon 还可以
产品编号 TMAY-02131F

Anti-CD19 Antibody-FITC (1T602) 是一种 FITC-conjugated Mouse 抗体,靶向 CD19。Anti-CD19 Antibody-FITC (1T602) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD19 Antibody-FITC (1T602) is a FITC-conjugated Mouse antibody targeting CD19. Anti-CD19 Antibody-FITC (1T602) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
1T602
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD19 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD19 and PE-conjugated anti-Human CD3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD19 (rh CD19; TMPY-01949; P15391-1; Met1-Lys291) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/Biotin/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human CD19 Protein (TMPY-01949)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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