Name: Izalontamab
Brand: TargetMol
SKU: T77047
Price: 5390 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 5,390

现货

5 mg

¥ 10,900

现货

10 mg

¥ 14,700

现货

生物活性

产品描述	Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers, thereby blocking downstream pathways. It is applicable for locally advanced or metastatic epithelial tumours, such as non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC).
体内活性	Izalontamab (5-46 mg/kg，静脉注射，每 7 天 1 次，共 4 次) 对携带SW48、FaDu和KYSE-150异种移植瘤的雌性NOD/SCID小鼠具有显著的抗肿瘤疗效。[1]
别名	依隆妥单抗, SI-B001, SIB001
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

储存&溶解度

存储	store at low temperature \| store at -20°C \| Shipping with blue ice/Shipping at ambient temperature.

Izalontamab