购物车
- 全部删除
您的购物车当前为空
Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
还可以产品编号 TMAY-03104
Anti-IL-36 alpha/IL-1F6 Antibody (3I744) 是一种 Rabbit 抗体，靶向 IL-36 alpha/IL-1F6。Anti-IL-36 alpha/IL-1F6 Antibody (3I744) 可用于 ELISA。
Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
还可以产品编号 TMAY-03104
Anti-IL-36 alpha/IL-1F6 Antibody (3I744) 是一种 Rabbit 抗体，靶向 IL-36 alpha/IL-1F6。Anti-IL-36 alpha/IL-1F6 Antibody (3I744) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-36 alpha/IL-1F6 Antibody (3I744) is a Rabbit antibody targeting IL-36 alpha/IL-1F6. Anti-IL-36 alpha/IL-1F6 Antibody (3I744) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3I744 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-1F6 (rM IL-1F6; TMPY-01956; Q9JLA2-1; Met1-His160). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. It has been reported that IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB in an IL-1Rrp2-dependent manner in Jurkat cells as well as in multiple other human and mouse cell lines. Activation of the pathway leading to NF-kappaB by IL-1F6 and IL-1F8 follows a similar time course to activation by IL-1beta, suggesting that signaling by the novel family members occurs through a direct mechanism. In a mammary epithelial cell line, NCI/ADR-RES, which naturally expresses IL-1Rrp2, all three cytokines signal without further receptor transfection. IL-1Rrp2 antibodies block activation of the pathway leading to NF-kappaB by IL-1F6, IL-1F8, and IL-1F9 in both Jurkat and NCI/ADR-RES cells. Thus IL-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse IL-1F6 Protein (TMPY-01956) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-IL-36 alpha/IL-1F6 Antibody (3I744) | purchase Anti-IL-36 alpha/IL-1F6 Antibody (3I744) | Anti-IL-36 alpha/IL-1F6 Antibody (3I744) cost | order Anti-IL-36 alpha/IL-1F6 Antibody (3I744)
嗨！有任何问题？点我咨询
评论内容