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Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335)
还可以产品编号 TMAY-02251
Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) 是一种 Mouse 抗体，靶向 KLH/Keyhole Limpet Hemocyanin。Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) 可用于 WB,ELISA。
Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335)
Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335)
还可以产品编号 TMAY-02251
Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) 是一种 Mouse 抗体，靶向 KLH/Keyhole Limpet Hemocyanin。Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) 可用于 WB,ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) is a Mouse antibody targeting KLH/Keyhole Limpet Hemocyanin. Anti-KLH/Keyhole Limpet Hemocyanin Antibody (6H335) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6H335 |
| 交叉反应 | other |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: his antibody can be used at 1:500-1:1000 with the appropriate secondary reagents to detect KLH in WB.; ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant KLH (Keyhole Limpet Hemocyanin). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | KLH (Keyhole Limpet Hemocyanin) is a copper-containing oxygen carrier occurring freely dissolved in the hemolymph of many mollusks and arthropods. KLH is used extensively as a carrier protein in the production of antibodies for research, biotechnology, and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins, and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production. KLH is the most widely employed carrier proteins for this purpose. It is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and the abundance of lysine residues for coupling haptens, allows a high hapten: carrier protein ratio increasing the likelihood of generating hapten-specific antibodies. KLH may also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic but limit the ability to conjugate haptens and are difficult to manipulate in the laboratory. A high-quality KLH preparation with a clear opalescent blue color is the best indicator of KLH solubility. KLH is being tested as a therapeutic vaccine for a variety of cancers, including non-Hodgkins lymphoma, cutaneous melanoma, breast, and bladder cancer. These vaccines use specific tumor-associated antigens (Haptens) conjugated to KLH to stimulate the body’s immune system to generate anti-tumor immune responses which can destroy tumor cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant KLH protein |
| 抗原种属 | other |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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