购物车
- 全部删除
您的购物车当前为空
Anti-Cathepsin D Antibody (8K856)
还可以产品编号 TMAY-02373
Anti-Cathepsin D Antibody (8K856) 是一种 Rabbit 抗体，靶向 Cathepsin D。Anti-Cathepsin D Antibody (8K856) 可用于 ELISA,ICC/IF。
Anti-Cathepsin D Antibody (8K856)
Anti-Cathepsin D Antibody (8K856)
还可以产品编号 TMAY-02373
Anti-Cathepsin D Antibody (8K856) 是一种 Rabbit 抗体，靶向 Cathepsin D。Anti-Cathepsin D Antibody (8K856) 可用于 ELISA,ICC/IF。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Cathepsin D Antibody (8K856) is a Rabbit antibody targeting Cathepsin D. Anti-Cathepsin D Antibody (8K856) can be used in ELISA,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8K856 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of CTSD in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human CTSD monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| 应用 | ELISA,ICC/IF |
| 推荐剂量 | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Cathepsin D / CTSD (rh Cathepsin D / CTSD; TMPY-02450; P07339; Met1-Leu412). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly described function is intracellular catabolism in lysosomal compartments, other physiological effect include hormone and antigen processing. Cathepsin D has a specificity similar to but narrower than that of pepsin A. Cathepsin D plays an important role in the degradation of proteins, the generation of bioactive proteins, antigen processing, etc. Among different role in cell physiology, a new function of this enzyme is examined. Cathepsin D is an important regulator of apoptotic pathways in cells. It acts at different stage of intrinsic and extrinsic pathway of apoptosis. In addition, CTSD secreted from human prostate carcinoma cells are responsible for the generation of angiostatin, a potent endogenous inhibitor of angiogenesis, suggesting its contribution to the prevention of tumor growth and angiogenesis-dependent growth of metastases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Cathepsin D / CTSD protein (TMPY-02450) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Cathepsin D Antibody (8K856) | purchase Anti-Cathepsin D Antibody (8K856) | Anti-Cathepsin D Antibody (8K856) cost | order Anti-Cathepsin D Antibody (8K856)
嗨！有任何问题？点我咨询
评论内容