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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho1 Polyclonal Antibody

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货号 TMAB-10276

Anti-Phospho1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho1。Anti-Phospho1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho1 Polyclonal Antibody

Anti-Phospho1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10276

Anti-Phospho1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho1。Anti-Phospho1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho1 Polyclonal Antibody is a Rabbit antibody targeting Phospho1. Anti-Phospho1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed at sites of mineralization in bone and cartilage. Highly expressed in osteoblast cell line SaOS-2 which produces a mineralized matrix, but not in MG-63 cell line, which do not mineralize.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PHOSPHO1 is a 267 amino acid phosphatase that is a member of the haloacid dehalogenase (HAD) superfamily of magnesium-dependent hydrolases. PHOSPHO1 is highly expressed in bone and cartilage and localizes to the osteoid layer of the periosteum. PHOSPHO1 is restricted to sites of mineralization and its inhibition decreases the ability of matrix vesicles to calcify in bone, suggesting that the protein may play a role in the matrix mineralization process during skeletal development. PHOSPHO1 cleaves phosphoethanolamine and phosphocholine to generate inorganic phosphate for bone mineralization. PHOSPHO1 contains three catalytic motifs that are conserved within the haloacid dehalogenase superfamily.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Phospho1
抗原种属
Human
基因名称
PHOSPHO1
基因ID
162466
蛋白名称
Phosphoethanolamine/phosphocholine phosphatase
Uniprot ID
Q8TCT1
功能
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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