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Anti-EGFR Antibody (6P389)
还可以产品编号 TMAY-00024
别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Anti-EGFR Antibody (6P389) 是一种 Rabbit 抗体，靶向 EGFR。Anti-EGFR Antibody (6P389) 可用于 ELISA,ELISA(Det),ICC/IF。
Anti-EGFR Antibody (6P389)
Anti-EGFR Antibody (6P389)
还可以产品编号 TMAY-00024 别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Anti-EGFR Antibody (6P389) 是一种 Rabbit 抗体，靶向 EGFR。Anti-EGFR Antibody (6P389) 可用于 ELISA,ELISA(Det),ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-EGFR Antibody (6P389) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (6P389) can be used in ELISA,ELISA(Det),ICC/IF. |
| 别名 | PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6P389 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human EGFR in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human EGFR monoclonal antibody (1:300) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). |
| 应用 | ELISA,ELISA(Det),ICC/IF |
| 推荐剂量 | ELISA: 1:25000-1:50000; ICC-IF: 1:100-1:500; ELISA(Det): 1:5000-1:50000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR (rh EGFR; TMPY-00742; Met 1-Ser 645; NP_005219) . |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human EGFR Protein（Catalog#10001-H08H） |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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