购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空

Anti-TROP-2 Antibody-HRP (7D257)

Rating icon 还可以
产品编号 TMAY-00814H

Anti-TROP-2 Antibody-HRP (7D257) 是一种 HRP-conjugated Mouse 抗体,靶向 TROP-2。Anti-TROP-2 Antibody-HRP (7D257) 可用于 ELISA。

Anti-TROP-2 Antibody-HRP (7D257)

Anti-TROP-2 Antibody-HRP (7D257)

Rating icon 还可以
产品编号 TMAY-00814H

Anti-TROP-2 Antibody-HRP (7D257) 是一种 HRP-conjugated Mouse 抗体,靶向 TROP-2。Anti-TROP-2 Antibody-HRP (7D257) 可用于 ELISA。

TargetMol
产品信息正在更新中,如果您想购买,请点击大包装&定制按钮.
大包装 & 定制
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载

产品介绍

生物活性
产品描述
Anti-TROP-2 Antibody-HRP (7D257) is a HRP-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-HRP (7D257) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
7D257
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TROP2 extracellular domain (rh TROP2; TMPY-01262; NP_002344.2; Met 1-Thr 274). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated/Biotin/FITC/PE
可提供抗体种类
5
抗原信息
免疫原
Recombinant Human TROP2 protein (TMPY-01262)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

SCI 文献

计算器

  • 稀释 计算器

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

Related Tags: buy Anti-TROP-2 Antibody-HRP (7D257) | purchase Anti-TROP-2 Antibody-HRP (7D257) | Anti-TROP-2 Antibody-HRP (7D257) cost | order Anti-TROP-2 Antibody-HRP (7D257)