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CD42b/GP1BA Protein, Human, Recombinant (aa 17-531, His) is expressed in HEK293 Cells. The accession number is P07359.


| 生物活性 | Immobilized Human CD42b, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA. |
| 产品描述 | CD42b/GP1BA Protein, Human, Recombinant (aa 17-531, His) is expressed in HEK293 Cells. The accession number is P07359. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | P07359 |
| 别名 | VWDP,GPIbα,GPIbalpha,GPIbA,GP1B,glycoprotein Ib (platelet), α polypeptide,glycoprotein Ib (platelet), alpha polypeptide,DBPLT3,CD42b-α,CD42b-alpha,CD42B,BSS,BDPLT3,BDPLT1 |
| 蛋白构建 | His17-Leu531 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 分子量 | 57.6 kDa (Predicted); 110-115 kDa (Due to glycosylation) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**. |