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Anti-ACVR1 Monoclonal Antibody (8B228)

Synonyms: TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI
货号 TMAT-0024 一键复制产品信息
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Anti-ACVR1 Monoclonal Antibody (8B228) 是一种 Mouse 抗体,靶向 ACVR1。Anti-ACVR1 Monoclonal Antibody (8B228) 可用于 IHC,IF,FCM。

Anti-ACVR1 Monoclonal Antibody (8B228)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0024

别名 TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI

Anti-ACVR1 Monoclonal Antibody (8B228) 是一种 Mouse 抗体,靶向 ACVR1。Anti-ACVR1 Monoclonal Antibody (8B228) 可用于 IHC,IF,FCM。

Anti-ACVR1 Monoclonal Antibody (8B228)
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产品介绍


生物活性
产品描述
Anti-ACVR1 Monoclonal Antibody (8B228) is a Mouse antibody targeting ACVR1. Anti-ACVR1 Monoclonal Antibody (8B228) can be used in IHC,IF,FCM.
别名
TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI
Ig Type
IgG1
克隆号
8B228
反应种属
Human
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. Coli.
抗原种属
Human
基因名称
ACVR1
基因ID
蛋白名称
Activin receptor type-1
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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