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Anti-Carboxypeptidase B2 Antibody (9H703)
还可以产品编号 TMAY-03501
Anti-Carboxypeptidase B2 Antibody (9H703) 是一种 Rabbit 抗体，靶向 Carboxypeptidase B2。Anti-Carboxypeptidase B2 Antibody (9H703) 可用于 ELISA。
Anti-Carboxypeptidase B2 Antibody (9H703)
Anti-Carboxypeptidase B2 Antibody (9H703)
还可以产品编号 TMAY-03501
Anti-Carboxypeptidase B2 Antibody (9H703) 是一种 Rabbit 抗体，靶向 Carboxypeptidase B2。Anti-Carboxypeptidase B2 Antibody (9H703) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Carboxypeptidase B2 Antibody (9H703) is a Rabbit antibody targeting Carboxypeptidase B2. Anti-Carboxypeptidase B2 Antibody (9H703) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9H703 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carboxypeptidase B2 / CPB2 (TMPY-02505; Q9JHH6; Met1-Thr422). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carboxypeptidase B2, also known as Carboxypeptidase U, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, CPB2, is a secreted protein which belongs to the peptidase M14 family. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by thrombin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin / thrombomodulin complex. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. CPB2 exhibits carboxypeptidase activity and activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Carboxypeptidase B2 / CPB2 protein (TMPY-02505) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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