CYP2C19 Protein, Human, Recombinant (His & Myc)

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产品编号 TMPH-01185

CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

CYP2C19 Protein, Human, Recombinant (His & Myc)

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产品编号 TMPH-01185

CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

规格	价格	库存
5 μg	¥ 656	3日内发货
10 μg	¥ 1,070	3日内发货
20 μg	¥ 1,800	现货
50 μg	¥ 2,730	20日内发货
100 μg	¥ 3,760	20日内发货
200 μg	¥ 5,780	20日内发货
500 μg	¥ 9,870	20日内发货
1 mg	¥ 16,000	20日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
种属	Human
表达系统	E. coli
标签	N-10xHis, C-Myc
蛋白编号	P33261
别名	Mephenytoin 4-hydroxylase,Fenbendazole monooxygenase (4'-hydroxylating),Cytochrome P450-254C,Cytochrome P450-11A,Cytochrome P450 2C19,CYPIIC19,CYPIIC17,CYP2C19,(S)-limonene 7-monooxygenase,(S)-limonene 6-monooxygenase,(R)-limonene 6-monooxygenase
氨基酸序列	RGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV
蛋白构建	26-490 aa
蛋白纯度	> 85% as determined by SDS-PAGE.
分子量	60.6 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Tris-based buffer, 50% glycerol
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates PUFA specifically at the omega-1 position. Catalyzes the epoxidation of double bonds of PUFA. Also metabolizes plant monoterpenes such as limonene. Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol. Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. Hydroxylates fenbendazole at the 4' position.