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顶部生物活性储存和溶解信息计算器

Anti-PDCD4 Antibody (2Z441)

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产品编号 TMAC-03109

别名 Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731

Anti-PDCD4 Antibody (2Z441) 是一种 Rabbit 抗体，靶向 PDCD4。Anti-PDCD4 Antibody (2Z441) 可用于 FCM,ICC,IHC,WB。

Anti-PDCD4 Antibody (2Z441)

Anti-PDCD4 Antibody (2Z441)

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产品编号 TMAC-03109 别名 Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731

Anti-PDCD4 Antibody (2Z441) 是一种 Rabbit 抗体，靶向 PDCD4。Anti-PDCD4 Antibody (2Z441) 可用于 FCM,ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDCD4 Antibody (2Z441) is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Antibody (2Z441) can be used in FCM,ICC,IHC,WB.
别名Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731
Ig Type
IgG
克隆号
2Z441
交叉反应
Human,Mouse
应用FCMICCIHCWB
推荐剂量
WB: 1:500; IHC: 1:50-200; ICC: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The transformation suppressor gene Pdcd-4 (programmed cell death gene 4) inhibits the tumor-promoter mediated transformation of mouse keratinocytes and is a potential tumor suppressor gene in the development of human lung cancer. Biochemical analysis suggests that the Pdcd-4 protein is involved in protein translation as well as in nuclear events. Pdcd-4 directly interacts with the RNA helicase eIF4A and inhibits protein synthesis by interfering with the assembly of the cap-dependent translation initiation complex. Pdcd-4 also suppresses the transactivation of AP-1 responsive promoters by c-Jun, suggesting that the transformation-suppressor activity of Pdcd-4 might be due, at least in part, to the inhibition of c-Jun activity. In addition to affecting c-Jun phosphorylation, Pdcd-4 blocks the recruitment of the co-activator p300 by c-Jun.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q53EL6
化学信息
分子量Theoretical: 52 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PDCD-4PDCD 4H-731H 731

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