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Anti-PDCD4 Antibody (2Z441)
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产品编号 TMAC-03109
别名 Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731
Anti-PDCD4 Antibody (2Z441) 是一种 Rabbit 抗体，靶向 PDCD4。Anti-PDCD4 Antibody (2Z441) 可用于 WB,ICC,IHC,FCM。
Anti-PDCD4 Antibody (2Z441)
Anti-PDCD4 Antibody (2Z441)
还可以产品编号 TMAC-03109 别名 Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731
Anti-PDCD4 Antibody (2Z441) 是一种 Rabbit 抗体，靶向 PDCD4。Anti-PDCD4 Antibody (2Z441) 可用于 WB,ICC,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-PDCD4 Antibody (2Z441) is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Antibody (2Z441) can be used in WB,ICC,IHC,FCM. |
| 别名 | Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 应用 | |
| 推荐剂量 | WB: 1:500; IHC: 1:50-200; ICC: 1:20-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The transformation suppressor gene Pdcd-4 (programmed cell death gene 4) inhibits the tumor-promoter mediated transformation of mouse keratinocytes and is a potential tumor suppressor gene in the development of human lung cancer. Biochemical analysis suggests that the Pdcd-4 protein is involved in protein translation as well as in nuclear events. Pdcd-4 directly interacts with the RNA helicase eIF4A and inhibits protein synthesis by interfering with the assembly of the cap-dependent translation initiation complex. Pdcd-4 also suppresses the transactivation of AP-1 responsive promoters by c-Jun, suggesting that the transformation-suppressor activity of Pdcd-4 might be due, at least in part, to the inhibition of c-Jun activity. In addition to affecting c-Jun phosphorylation, Pdcd-4 blocks the recruitment of the co-activator p300 by c-Jun. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 52 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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