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Anti-CD27/TNFRSF7 Antibody-FITC (3U92) 是一种 FITC-conjugated Mouse 抗体,靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody-FITC (3U92) 可用于 FCM。
Anti-CD27/TNFRSF7 Antibody-FITC (3U92) 是一种 FITC-conjugated Mouse 抗体,靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody-FITC (3U92) 可用于 FCM。
产品描述 | Anti-CD27/TNFRSF7 Antibody-FITC (3U92) is a FITC-conjugated Mouse antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody-FITC (3U92) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 3U92 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of anti-human CD27 on human whole blood lymphocytes. Human lymphocytes were stained with FITC-anti human CD27 (solid line) or FITC-Mouse IgG isotype control (dashed line). |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD27 / TNFRSF7 (rh CD27 / TNFRSF7; NP_001233.1Met 1-Ile 192) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PerCP/PE |
可提供抗体种类 | 5 |
免疫原 | Recombinant Human CD27 / TNFRSF7 protein |
抗原种属 | Human |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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