Buprofezin

Name: Buprofezin
Brand: TargetMol
SKU: T3496
Price: 198 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.73%

货号 T3496Cas号 69327-76-0

别名 噻嗪酮, NNI 750, Buprofezine, Applaud

Buprofezin (Applaud) 是一种杀虫剂，通过抑制几丁质合成起作用，在体外还可以剂量依赖性地增加活性氧的产生。

Buprofezin

一键复制产品信息

很棒

纯度: 99.73%

货号 T3496 别名 噻嗪酮, NNI 750, Buprofezine, ApplaudCas号 69327-76-0

Buprofezin (Applaud) 是一种杀虫剂，通过抑制几丁质合成起作用，在体外还可以剂量依赖性地增加活性氧的产生。

规格	价格	库存
25 mg	¥ 198	现货
50 mg	¥ 343	现货
100 mg	¥ 578	现货
200 mg	¥ 849	现货
500 mg	¥ 1,420	现货

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产品介绍

Buprofezin AI Summary

Buprofezin exhibits a wide range of bioactivities and significant insecticidal properties. It functions as an estrogen receptor alpha agonist while acting as an antagonist for thyroid hormone receptor beta, farnesoid X receptor, androgen receptor, peroxisome proliferator-activated receptor gamma, and retinoid X receptor alpha signaling pathways. Additionally, it activates peroxisome proliferator-activated receptor delta, peroxisome proliferator-activated receptor gamma, vitamin D receptor, antioxidant response element (ARE), and human pregnane X receptor (PXR) signaling pathways. In terms of insecticidal activity, Buprofezin is highly effective against Bemisia tabaci (sweet potato whitefly), showing potency across various life stages by affecting offspring sex ratio, longevity, and egg hatch rate, with higher concentrations yielding greater mortality rates. It is also efficacious against various hybrids, generations, and buprofezin-resistant populations of Bemisia tabaci. The compound demonstrates significant insecticidal effectiveness against Encarsia inaron, particularly when applied to larval stages at 31.25 ppm, reducing sex ratio, egg-laying rate, and longevity. When applied to cucumber plants infested with Encarsia inaron, it reduces adult parasitoid emergence, especially at pupal stages. Noteworthy is its acute toxicity observed in female adult Anagrus nilaparvatae, with 29.4% mortality from oral administration and minimal residual toxicity (1.1%) from compound-treated rice leaves. Its acute contact toxicity LC50 for adult Anagrus nilaparvatae is above 1000.0 mgAi/L, indicating relatively low contact toxicity. Buprofezin also shows substantial activity against first-instar larvae of Cheumatopsyche brevilineata with an EC50 value of 0.181 ug/mL and demonstrates a lower, yet notable, toxicity towards Daphnia magna. The compound has a high partition coefficient (log KOW of 4.3), indicating good solubility in both water and organic phases. Furthermore, the compound affects Nilaparvata lugens (brown planthopper) by impacting lifespan, ovariole development, egg maturity, hatchability, and oviposition. It induces mortality in brown planthopper adults and fifth-instar nymphs in a concentration-dependent manner over 7 days of exposure..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.
别名	噻嗪酮, NNI 750, Buprofezine, Applaud

化学信息

分子量	305.44
分子式	C₁₆H₂₃N₃OS
CAS No.	69327-76-0
Smiles	C(C)(C)N1C(=NC(C)(C)C)SCN(C1=O)C2=CC=CC=C2
密度	1.18 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (163.7 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.55 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2740 mL	16.3698 mL	32.7397 mL	163.6983 mL
5 mM	0.6548 mL	3.2740 mL	6.5479 mL	32.7397 mL
10 mM	0.3274 mL	1.6370 mL	3.2740 mL	16.3698 mL
20 mM	0.1637 mL	0.8185 mL	1.6370 mL	8.1849 mL
50 mM	0.0655 mL	0.3274 mL	0.6548 mL	3.2740 mL
100 mM	0.0327 mL	0.1637 mL	0.3274 mL	1.6370 mL