Anti-CD19 Antibody (2Y62)

Name: Anti-CD19 Antibody (2Y62)
Brand: TargetMol
SKU: TMAY-02132
Rating: 4.5 (1 reviews)

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产品编号 TMAY-02132

Anti-CD19 Antibody (2Y62) 是一种 Mouse 抗体，靶向 CD19。Anti-CD19 Antibody (2Y62) 可用于 IHC-P。

Anti-CD19 Antibody (2Y62)

还可以

产品编号 TMAY-02132

Anti-CD19 Antibody (2Y62) 是一种 Mouse 抗体，靶向 CD19。Anti-CD19 Antibody (2Y62) 可用于 IHC-P。

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生物活性

产品描述	Anti-CD19 Antibody (2Y62) is a Mouse antibody targeting CD19. Anti-CD19 Antibody (2Y62) can be used in IHC-P.
Ig Type	Monoclonal Mouse IgG2a
克隆号	2Y62
交叉反应	Human
验证活性	1. Immunochemical staining of human CD19 in human tonsil with mouse monoclonal antibody(11:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD19 in human spleen with mouse monoclonal antibody(11:200, formalin-fixed paraffin embedded sections).
应用	IHC-P
推荐剂量	IHC-P: 1:50-1:200
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD19 (rh CD19; TMPY-01949; P15391-1; Met1-Lys291). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human CD19 Protein (TMPY-01949)
抗原种属	Human
研究领域	Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.