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Anti-Pan Cytokeratin Antibody (7X356) 是一种 Mouse 抗体,靶向 Pan Cytokeratin。Anti-Pan Cytokeratin Antibody (7X356) 可用于 IHC-P,IHC-Fr,IF。
Anti-Pan Cytokeratin Antibody (7X356) 是一种 Mouse 抗体,靶向 Pan Cytokeratin。Anti-Pan Cytokeratin Antibody (7X356) 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 3 mL | ¥ 540 | 5日内发货 | |
| 6 mL | ¥ 975 | 5日内发货 |
| 产品描述 | Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG2b |
| 克隆号 | 7X356 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasmic. |
| 组织特异性 | epithelial cells |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| 研究背景 | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection. |
| 免疫原 | KLH conjugated synthetic peptide: human Pan Cytokeratin |
| 抗原种属 | Human |
| 基因名称 | KRT24 |
| 基因ID | |
| 蛋白名称 | Keratin, type I cytoskeletal 24 |
| Uniprot ID |
| 分子量 | Theoretical: 42-64 kDa. |
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |