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Anti-SLC4A4 Polyclonal Antibody 2

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货号 TMAB-12907

Anti-SLC4A4 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SLC4A4。Anti-SLC4A4 Polyclonal Antibody 2 可用于 WB。

Anti-SLC4A4 Polyclonal Antibody 2

Anti-SLC4A4 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-12907

Anti-SLC4A4 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SLC4A4。Anti-SLC4A4 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-SLC4A4 Polyclonal Antibody 2 is a Rabbit antibody targeting SLC4A4. Anti-SLC4A4 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Basolateral cell membrane; Multi-pass membrane protein.
组织特异性Isoform 1 is expressed in pancreas and to a lower extent in heart, skeletal muscle, liver, parotid salivary glands, prostate, colon, stomach, thyroid, brain and spinal chord. Corneal endothelium cells express only isoform 1 (at protein level). Isoform 2 is specifically expressed in kidney at the level of proximal tubules.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SLC4A4 (Electrogenic sodium bicarbonate cotransporter 1) is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. It may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. SLC4A4 interacts with carbonic anhydrase 2 and carbonic anhydrase 4 which may regulate transporter activity. There are four named isoforms produced by alternative splicing. This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human SLC4A4 isoform 2
抗原种属
Human
基因名称
SLC4A4
基因ID
8671
蛋白名称
Electrogenic sodium bicarbonate cotransporter 1
Uniprot ID
Q9Y6R1
功能
Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.
化学信息
分子量Theoretical: 116 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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