规格

价格

库存

数量

5 μg

¥ 543

3日内发货

10 μg

¥ 888

3日内发货

20 μg

¥ 1,470

3日内发货

50 μg

¥ 2,930

现货

100 μg

¥ 5,010

5日内发货

200 μg

¥ 8,560

5日内发货

500 μg

¥ 17,300

5日内发货

生物活性

产品描述	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
生物活性	Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.8-3.3 μg/mL.
研究背景	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P55075-2
蛋白构建	A DNA sequence encoding the human FGF8a (NP_149355.1) (Gln23-Arg204) was expressed with an initial Met. Predicted N terminal: Met
蛋白纯度	> 95 % as determined by SDS-PAGE.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, pH 8.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.13 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	NEWENTRY, KAL6, HH6, HBGF-8, fibroblast growth factor 8 (androgen-induced), FGF-8, AIGF
内毒素	Please contact us for more information.

化学信息

分子量	21.3 kDa (predicted)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

FGF-8a Protein, Human, Recombinant

FGF-8a Protein, Human, Recombinant

产品介绍

计算器

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引用文献

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