VU534 (30 μM; 24 h) is less cytotoxic to HepG2 and Raw264.7 cell lines.[1]
VU534 (3~30 μM; 1 h) can increase NAPE-PLD activity in Raw264.7 cells.[1]
VU534 (1 h) can increase NAPE-PLD activity in HepG2 cells with an EC50 value of 1.5 μM.[1]
VU534 (5 μM, 1 h) increased NAPE-PLD activity 1.5-fold but did not reverse NAPE-PLD activity inhibited by LEI–401.[1]
VU534 (10 μM; 6 h) significantly enhances efferocytosis of bone marrow-derived macrophages but cannot exert this effect when Napepld is knocked out.[1]