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Anti-MALT1 Antibody (4D932)

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货号 TMAB-08537

Anti-MALT1 Antibody (4D932) 是一种 Rabbit 抗体,靶向 MALT1。Anti-MALT1 Antibody (4D932) 可用于 WB,ICC/IF,FCM。

Anti-MALT1 Antibody (4D932)

Anti-MALT1 Antibody (4D932)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08537

Anti-MALT1 Antibody (4D932) 是一种 Rabbit 抗体,靶向 MALT1。Anti-MALT1 Antibody (4D932) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-MALT1 Antibody (4D932) is a Rabbit antibody targeting MALT1. Anti-MALT1 Antibody (4D932) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
4D932
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, perinuclear region. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
组织特异性Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines.
抗原信息
免疫原
A synthesized peptide: human MALT1
抗原种属
Human
基因名称
MALT1
基因ID
蛋白名称
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Uniprot ID
功能
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
化学信息
分子量Theoretical: 92 kDa. Actual: 92 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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