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Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

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货号 TMPY-03878U

别名 ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)
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Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

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货号 TMPY-03878U 别名 ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).

规格价格库存数量
5 μg
¥ 562
6-8日内发货
10 μg
¥ 918
6-8日内发货
20 μg
¥ 1,520
5日内发货
50 μg
¥ 2,970
5日内发货
100 μg
¥ 5,120
5日内发货
200 μg
¥ 9,030
5日内发货
500 μg
¥ 19,000
5日内发货
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产品介绍


生物活性
产品描述
Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).
生物活性
Immobilized Human ITGAV&ITGB6, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.49 μg/ml determined by ELISA.
研究背景
ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号P06756-1(ITGAV)&P18564-1(ITGB6)
蛋白构建Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量114 kDa (ITGAV) & 79.1 kDa (ITGB6) (Predicted); 90-150 kDa (Due to glycosylation)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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