Name: Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)
Brand: TargetMol
SKU: TMPY-03878U
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 562

6-8日内发货

10 μg

¥ 918

6-8日内发货

20 μg

¥ 1,520

5日内发货

50 μg

¥ 2,970

5日内发货

100 μg

¥ 5,120

5日内发货

200 μg

¥ 9,030

5日内发货

500 μg

¥ 19,000

5日内发货

生物活性

产品描述	Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).
生物活性	Immobilized Human ITGAV&ITGB6, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.49 μg/ml determined by ELISA.
研究背景	ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P06756-1(ITGAV)&P18564-1(ITGB6)
蛋白构建	Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	114 kDa (ITGAV) & 79.1 kDa (ITGB6) (Predicted); 90-150 kDa (Due to glycosylation)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

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