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Anti-DKC1 Antibody (9U209) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (9U209) 可用于 WB,ICC,IF,IHC。
Anti-DKC1 Antibody (9U209) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (9U209) 可用于 WB,ICC,IF,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-DKC1 Antibody (9U209) is a Rabbit antibody targeting DKC1. Anti-DKC1 Antibody (9U209) can be used in WB,ICC,IF,IHC. |
别名 | XAP101, XAP 101, snoRNP protein DKC1, Nucleolar protein NAP57, Nucleolar protein family A member 4, Nopp140-associated protein of 57 kDa, Nopp140 associated protein of 57 kDa, NOLA4, NOLA 4, NAP57, NAP 57, H/ACA ribonucleoprotein complex subunit 4, Dyskerin, Dyskeratosis congenita 1 dyskerin, Dyskeratosis congenita 1, DKCX, DKC1_HUMAN, Dkc1, DKC 1, DKC, Cbf5p homolog, CBF5 homolog, CBF5 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of DKC1 on A431 cell lysate using anti-DKC1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DKC1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-DKC1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-DKC1 antibody. Counter stained with hematoxylin. 5. ICC staining DKC1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-100; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Isoform 3: Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells). |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 57 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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