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Anti-AGR2 Antibody (8A267)

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货号 TMAB-02386

Anti-AGR2 Antibody (8A267) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (8A267) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-AGR2 Antibody (8A267)

Anti-AGR2 Antibody (8A267)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02386

Anti-AGR2 Antibody (8A267) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (8A267) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-AGR2 Antibody (8A267) is a Rabbit antibody targeting AGR2. Anti-AGR2 Antibody (8A267) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
8A267
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:20-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted. Endoplasmic reticulum.
组织特异性Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AGR2 is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and ?dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.
抗原信息
免疫原
A synthesized peptide: human AGR2
抗原种属
Human
基因名称
AGR2
基因ID
蛋白名称
Anterior gradient protein 2 homolog
Uniprot ID
功能
Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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