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Anti-AGR2 Antibody (8A267) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (8A267) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-AGR2 Antibody (8A267) 是一种 Rabbit 抗体,靶向 AGR2。Anti-AGR2 Antibody (8A267) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-AGR2 Antibody (8A267) is a Rabbit antibody targeting AGR2. Anti-AGR2 Antibody (8A267) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 8A267 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:20-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. Endoplasmic reticulum. |
| 组织特异性 | Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | AGR2 is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and ?dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers. |
| 免疫原 | A synthesized peptide: human AGR2 |
| 抗原种属 | Human |
| 基因名称 | AGR2 |
| 基因ID | |
| 蛋白名称 | Anterior gradient protein 2 homolog |
| Uniprot ID | |
| 功能 | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. |
| 分子量 | Theoretical: 20 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |