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Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ADAM17 (Thr735)。Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 可用于 WB。
Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ADAM17 (Thr735)。Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ADAM17 (Thr735). Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody can be used in WB. |
别名 | p-ADAM17 (Thr735), p-ADAM17 (T735), ADAM17 (p-Thr735), ADAM17 (p-T735) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from K562 cells treated with UV using ADAM 17 (Phospho-Thr735) Antibody TMAC-00084.The lane on the left is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of Threonine 735 (P-Q-T(p)-P-G) derived from Human ADAM 17 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 93 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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